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| Folate receptor α deficiency – Myelin‐sensitive MRI as a reliable biomarker to monitor the efficacy and long‐term outcome of a new therapeutic approach |
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| H3 Acetylation-Induced Basal Progenitor Generation and Neocortex Expansion Depends on the Transcription Factor Pax6 |
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| Transient Non-local Interactions Dominate the Dynamics of Measles Virus N TAIL |
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| The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish |
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| The plasma miRNAome in ADNI: Signatures to aid the detection of at‐risk individuals |
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| Lead as a toxic environmental toxicant in models of synucleinopathies |
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| Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria |
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| Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants |
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| Rational Approximation of Golden Angles for Simple and Reproducible Radial Sampling |
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| Endogenous tagging of Munc13-1 with a SNAP tag as a tool for monitoring synapse nanoarchitecture |
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| Uncovering potential diagnostic and pathophysiological roles of α‐synuclein and DJ‐1 in melanoma |
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| The synaptic vesicle cluster as a controller of pre‐ and postsynaptic structure and function |
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| Mechanism of polyadenylation-independent RNA polymerase II termination |
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| Drosophila MIC10b can polymerize into cristae-shaping filaments |
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| Membrane Tension Regulation is Required for Wound Repair |
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| Cytoarchitecture of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography: imaging workflow and classification for drug testing |
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| Super-Resolution Axial Imaging for Quantifying Piconewton Traction Forces in Live-cells |
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| Expansion of the complex genotypic and phenotypic spectrum of FGFR2-associated neurocutaneous syndromes |
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| Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations |
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| BCAS1-positive oligodendrocytes enable efficient cortical remyelination in multiple sclerosis |
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| A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features |
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| Characterizing ATP processing by the AAA+ protein p97 at the atomic level |
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| CryoRhodopsins: a comprehensive characterization of a new clade of microbial rhodopsins from cold environments |
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| Impact of Phosphorylation on the Physiological Form of Human alpha-Synuclein in Aqueous Solution |
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| Identifiability of the Optimal Transport Cost on Finite Spaces |
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| Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants |
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| Model-Based Reconstruction for Joint Estimation of $T_{1}$, $R_{2}^{*}$ and $B_{0}$ Field Maps Using Single-Shot Inversion-Recovery Multi-Echo Radial FLASH |
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| Bridging the gap between presynaptic hair cell function and neural sound encoding |
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| In-situ architecture of the human prohibitin complex |
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| Two mechanisms repress cyclin B1 translation to maintain prophase arrest in mouse oocytes |
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| Mouse oocytes sequester aggregated proteins in degradative super-organelles |
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| Nonlinear receptive fields evoke redundant retinal coding of natural scenes |
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| Near-optimal information relay by the neuronal population of layer 4 barrel cortex |
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| SynapseNet: Deep Learning for Automatic Synapse Reconstruction |
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| A metabolically controlled contact site between vacuoles and lipid droplets in yeast |
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| What should a neuron aim for? Designing local objective functions based on information theory |
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| RNA helicase IGHMBP2 regulates THO complex to ensure cellular mRNA homeostasis |
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| Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways |
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| Human serum-derived α-synuclein auto-antibodies mediate NMDA receptor-dependent degeneration of CNS neurons |
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| Measuring sub-nanometer undulations at microsecond temporal resolution with metal- and graphene-induced energy transfer spectroscopy |
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| Structure of the multi-subunit chloroplast RNA polymerase |
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| MultiMatch: Geometry-Informed Colocalization in Multi-Color Super-Resolution Microscopy |
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| Cytoarchitecture of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography: imaging workflow and classification for drug testing |
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| 3D Super-Resolution Nuclear Q-FISH Imaging Reveals Cell-Cycle-Related Telomere Changes |
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| Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies |
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| Cryo-EM structures of lipidic fibrils of amyloid-β (1-40) |
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| A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise |
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| Most discriminative stimuli for functional cell type clustering |
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| Recording ten-fold larger IKr conductances with automated patch clamping using equimolar Cs+ solutions |
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| Biallelic NAA60 variants with impaired n-terminal acetylation capacity cause autosomal recessive primary familial brain calcifications |
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| mtDNA Analysis using Mitopore |
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| NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals |
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| Hörvermögen wiederherstellen mit Optogenetik | | Moser T | Sprache-Stimme-Gehör | 2024 | | |
| Adsorption of alpha-synuclein and inhibition of fibril formation by nanocellulose and gold-coated-nanocellulose |
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| RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity |
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| Multiscale Quantile Regression with Local Error Control |
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| Formation of memory assemblies through the DNA-sensing TLR9 pathway |
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| Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice |
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| Gender-Specific Effects on the Cardiorespiratory System and Neurotoxicity of Intermittent and Permanent Low-Level Lead Exposures |
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| Robust inference of cooperative behaviour of multiple ion channels in voltage-clamp recordings |
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| [11C]MODAG 005 – a novel PET tracer targeting alpha-synuclein aggregates in the brain |
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| METTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway |
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| Structural basis of Integrator-dependent RNA polymerase II termination |
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| Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion |
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| Molecular basis of human nuclear and mitochondrial tRNA 3'-processing |
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| Super-resolution going viral: T4 virus particles as perfect nature-designed 3D-Bio-NanoRulers |
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| How Natural Enzymes and Synthetic Ribozymes Generate Methylated Nucleotides in RNA | | Höbartner C, Bohnsack KE, Bohnsack MT | Annual Review of Biochemistry | 2024 | | |
| Computational functions of precisely balanced neuronal assemblies in an olfactory memory network |
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| α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway |
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| Insights into cochlear structure by innovative light sheet fluorescence microscopy |
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| In situ studies of membrane biology by cryo-electron tomography |
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| Myosin II actively regulates Drosophila proprioceptors |
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| A role for astrocytic miR-129-5p in Frontotemporal Dementia |
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| Microtubules: highway to … arrhythmia? |
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| Cerebellar Ex Vivo Magnetic Resonance Imaging at its Feasibility Limit: Up to 77-Microns Isotropic Resolution using Low-Bandwidth Balanced Steady State Free Precession (LoBa-bSSFP) Sequences and 3T Standard Equipment |
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| Profiling the LAM family of contact site tethers provides insights into their regulation and function |
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| Click Chemistry with Cell-Permeable Fluorophores Expands the Choice of Bioorthogonal Markers for Two-Color Live-Cell STED Nanoscopy |
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| A subgroup of light-driven sodium pumps with an additional Schiff base counterion |
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| Variational calculus approach to Zernike polynomials with application to fluorescence correlation spectroscopy |
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| Basic Science in Movement Disorders: Fueling the Engine of Translation into Clinical Practice |
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| Generation of a pluripotent stem cell line (UMGi270-A) and a corresponding CRISPR/Cas9 modified isogenic control (UMGi270-A-1) from a patient with sudden onset dilated cardiomyopathy harboring a FLNC p.R2187P mutation |
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| Label-free quantification of imaging features in the extracellular matrix of left and right-sided colon cancer tissues |
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| 3D imaging of protein aggregates in human neurodegeneration by multiscale X-ray phase-contrast tomography |
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| Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14 Δ/+ mice hearts |
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| The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites |
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| Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in liver |
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| Unraveling haplotype errors in the DFNA33 locus |
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| Tazarotene and Bexarotene Show Efficacy as In Vitro Therapeutic Agents in Multiple Sulfatase Deficiency |
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| Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity |
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| NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming |
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| Defining the Riddle in Order to Solve It: There Is More Than One “Parkinson's Disease” |
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| Secreted-Frizzled-Related Protein 5 Modulates Calcium Handling in Human Ipsc-Cardiomyocytes |
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| Flotillin-Associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes |
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| The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system |
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| Applying Super-Resolution and Tomography Concepts to Identify Receptive Field Subunits in the Retina |
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| 3d Virtual Histology Reveals Pathological Alterations of Cerebellar Granule Cells in Multiple Sclerosis |
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| The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments |
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| A Bright Surprise: Live‐Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag |
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| Adaptive minimax optimality in statistical inverse problems via SOLIT -- Sharp Optimal Lepskii-Inspired Tuning |
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| Quantitative MRI by nonlinear inversion of the Bloch equations |
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| Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease |
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| Combining a Tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC) |
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| Ethanol-Induced Atrial Fibrillation Results From Late INa and Can Be Prevented by Ranolazine |
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| The Statistics of Circular Optimal Transport |
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| From Molecular to Functional Effects of Different Environmental Lead Exposure Paradigms |
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| Bridging the gap between presynaptic hair cell function and neural sound encoding |
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| Deep, deep learning with BART |
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| Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy |
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| Kantorovich–Rubinstein Distance and Barycenter for Finitely Supported Measures: Foundations and Algorithms |
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| Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane |
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| Unbalanced Kantorovich-Rubinstein distance and barycenter for finitely supported measures: A statistical perspective |
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| New Insights into the Proteolytic Regulation of the Structural Protein Junctophilin-2 by Calpain |
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| Editorial: Cardiac optogenetics: Using light to observe and excite the heart |
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| Sampling effects and measurement overlap can bias the inference of neuronal avalanches |
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| Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells |
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| Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp |
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| Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse |
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| Tackling the Dynamic Range Problem of Hearing: Diverse Hair Cell Synapses Enable Broad Neural Sound Intensity Coding |
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| Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II |
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| The Synaptic Extracellular Matrix: Long-Lived, Stable, and Still Remarkably Dynamic |
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| The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity |
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| The 3D structure of lipidic fibrils of α-synuclein |
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| Mono- and Intralink Filter (Mi-Filter) To Reduce False Identifications in Cross-Linking Mass Spectrometry Data |
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| Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain |
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| Two-color live-cell STED nanoscopy by click labeling with cell-permeable fluorophores |
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| Cotranslational Biogenesis of Membrane Proteins in Bacteria |
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| On the Fabrication and Characterization of Polymer-Based Waveguide Probes for Use in Future Optical Cochlear Implants |
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| The Role of Junctophilin Proteins in Cellular Function |
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| Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III specific assembly factor in mitochondria |
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| Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells |
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| Structural basis for safe and efficient energy conversion in a respiratory supercomplex |
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| The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds |
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| White matter integrity in mice requires continuous myelin synthesis at the inner tongue |
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| The ultrametric Gromov-Wasserstein distance |
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| 14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban | | Menzel J, Kownatzki-Danger D, (...), Schwappach B | Science Signaling | 2020 | | |
| Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex |
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| 3D analysis of the myenteric plexus of the human bowel by X-ray phase-contrast tomography – a future method? |
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| Investigating the Structure of Neurotoxic Protein Aggregates Inside Cells |
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| Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices |
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| Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity |
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| MOG-expressing teratoma followed by MOG-IgG-positive optic neuritis |
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| Optimistic search strategy: Change point detection for large-scale data via adaptive logarithmic queries |
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| Analysis of Patchclamp Recordings: Model-Free Multiscale Methods and Software |
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| Quantitative analysis of hidden particles diffusing behind a scattering layer using speckle correlation |
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| Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy |
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| Physics-based Reconstruction Methods for Magnetic Resonance Imaging |
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| Variational multiscale nonparametric regression: Algorithms |
| del Alamo M, Li H, Munk A, Werner F | arXiv | 2020 | | |
| 3D virtual histology of human pancreatic tissue by multiscale phase-contrast X-ray tomography |
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| Defining the architecture of the human TIM22 complex by chemical crosslinking |
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| Absolute quantum yield measurements of fluorescent proteins using a plasmonic nanocavity |
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| Pharmacological Modulators of Tau Aggregation and Spreading |
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| Variational Multiscale Nonparametric Regression: Algorithms and Implementation |
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| Viral rhodopsins 1 are an unique family of light-gated cation channels |
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| Randomised Wasserstein Barycenter Computation: Resampling with Statistical Guarantees |
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| Structural basis of nucleosome transcription mediated by Chd1 and FACT |
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| Cellular and mitochondrial mechanisms of atrial fibrillation |
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| The Coding And Small-Non-Coding Hippocampal Synaptic RNAome |
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| Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2 |
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| Heterogeneous Idealization of Ion Channel Recordings – Open Channel Noise |
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| Time-resolved MIET measurements of blood platelet spreading and adhesion |
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| X-Ray Structural Analysis of Single Adult Cardiomyocytes: Tomographic Imaging and Microdiffraction |
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| Multiple Haplotype Reconstruction from Allele Frequency Data |
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| Premature aging disorders: A clinical and genetic compendium |
| Schnabel F, Kornak U, Wollnik B | Clinical Genetics | 2020 | | |
| GROMEX: A Scalable and Versatile Fast Multipole Method for Biomolecular Simulation |
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| Bioprospection of Natural Sources of Polyphenols with Therapeutic Potential for Redox-Related Diseases |
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| 3D virtual pathohistology of lung tissue from Covid-19 patients based on phase contrast X-ray tomography |
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| The Role of Alpha-Synuclein and Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders |
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| Correction: Circumvention of common labelling artefacts using secondary nanobodies |
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| In situ architecture of neuronal α-Synuclein inclusions |
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| SETD1B controls cognitive function via cell type specific regulation of neuronal identity genes |
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| RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies |
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| Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization |
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| Local translation in synaptic mitochondria influences synaptic transmission |
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| Three-dimensional beating dynamics of Chlamydomonas flagella |
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| Novel Secondary Ion Mass Spectrometry Methods for the Examination of Metabolic Effects at the Cellular and Subcellular Levels |
| Bonnin EA, Rizzoli SO | Frontiers in Behavioral Neuroscience | 2020 | | |
| Minimax estimation in linear models with unknown design over finite alphabets |
| Behr M, Munk A | arXiv | 2020 | | |
| Gromov-Wasserstein Distance based Object Matching: Asymptotic Inference |
| Weitkamp CA, Proksch K, Tameling C, Munk A | arXiv | 2020 | | |
| Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations |
| Farnung L, Ochmann M, Cramer P | eLife | 2020 | | |
| Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis |
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| Fluorescence polarization filtering for accurate single molecule localization |
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| Editorial commentary: Challenges to heart repair with pluripotent stem cell-derived cardiomyocytes | | Zimmermann W | Trends in Cardiovascular Medicine | 2020 | | |
| Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.7 Å inside cells |
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| Generation of Engineered Human Myocardium in a Multi-well Format |
| Tiburcy M, Meyer T, Liaw NY, Zimmermann W | STAR Protocols | 2020 | | |
| Empirical Regularized Optimal Transport: Statistical Theory and Applications |
| Klatt M, Tameling C, Munk A | SIAM Journal on Mathematics of Data Science | 2020 | | |
| NETT: solving inverse problems with deep neural networks |
| Li H, Schwab J, Antholzer S, Haltmeier M | Inverse Problems | 2020 | | |
| Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system |
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| 19th Annual Meeting of the Safety Pharmacology Society: regulatory and safety perspectives for advanced therapy medicinal products (cellular and gene therapy products) | | Cavero I, Seimetz D, Koziel D, Zimmermann W, Holzgrefe HH | Expert Opinion on Drug Safety | 2020 | | |
| Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis |
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| De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome |
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| Vesicle adhesion in the electrostatic strong-coupling regime studied by time-resolved small-angle X-ray scattering |
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| Testing for dependence on tree structures |
| Behr M, Ansari MA, Munk A, Holmes C | Proceedings of the National Academy of Sciences of the United States of America | 2020 | | |
| White matter integrity requires continuous myelin synthesis at the inner tongue |
| Meschkat M, Steyer AM, (...), Möbius W | bioRxiv | 2020 | | |
| A Cross-linking Mass Spectrometry Approach Defines Protein Interactions in Yeast Mitochondria |
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| Human RAD50 deficiency: Confirmation of a distinctive phenotype |
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| Multi-scale X-ray phase-contrast tomography of murine heart tissue |
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| Fiber orientation in a whole mouse heart reconstructed by laboratory phase-contrast micro-CT |
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| Seeded Binary Segmentation: A general methodology for fast and optimal change point detection |
| Kovács S, Li H, Bühlmann P, Munk A | arXiv | 2020 | | |
| Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control |
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| JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties | | Fonseca-Fonseca LA, da Silva VDA, (...), Núñez-Figueredo Y | Neurotoxicology | 2020 | | |
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| Live-cell STED nanoscopy of mitochondrial cristae |
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| Macromolecular and electrical coupling between inner hair cells in the rodent cochlea |
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| The recurrent postzygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuroectodermal phenotype |
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| A combined miRNA-piRNA signature to detect Alzheimer's disease |
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| Modeling Fluorescence Correlation Spectroscopy through an aberrating sphere |
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| Empirical optimal transport on countable metric spaces: Distributional limits and statistical applications | | Tameling C, Sommerfeld M, Munk A | Annals of Applied Probability | 2019 | | |
| Circumvention of common labeling artifacts using secondary nanobodies |
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| The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers |
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| Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta | | Moosa S, Yamamoto GL, (...), Netzer C | American Journal of Human Genetics | 2019 | | |
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| Testing for dependence on tree structures |
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| Eukaryotic Transcription Turns 50 |
| Cramer P | Cell | 2019 | | |
| Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau |
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| Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome |
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| Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes |
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| Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity |
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| Multiscale quantile segmentation |
| Vanegas LJ, Behr M, Munk A | arXiv | 2019 | | |
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| The Essential Histogram |
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| Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation |
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| Frame-constrained Total Variation Regularization for White Noise Regression |
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| High-resolution experimental and computational electrophysiology reveals weak β-lactam binding events in the porin PorB |
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| Multiscale change-point segmentation: beyond step functions |
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